Classic Olde Tyme Typesetting

I found this wanted poster for John Wilkes Booth posted on Wikipedia today. Our predicessors had it much rougher than we.

Couple things I've noticed:
The many typefaces used.
The large spaces after period marks.
Paragraphs are justified (must have been a huge pain to do this by hand)
Inconsistent upper case and lower case usage
Inconsistent Indents.

With all of these issues with the poster it remains an effective piece of attention grabbing design. I really enjoy looking at old professional prints/typography such as this. I wonder, the difficulties and hardships typesetters of old had with setting up and producing a document like this where the errors I pointed out are accepted, did they actually have it tougher than us? We have more options, high standards, millions of colors, paper choices, printing choices, software, hardware, stupid clients and greater competition? Hm...